Spanning the web to bring you the awesome power of E. coli
Spanning the web to bring you the awesome power of E. coli
EcoliHub blog » EcoliHub:
by jimhu (2 weeks ago):
Information pertaining to the E. coli B strain known as REL606 (RefSeq NC_012967) is now available from EcoliWiki, so please add information about the strain or genes of interest. [Click here to see the gene list for REL606]. We’re still working on a few things, but if you see a problem please [...]
Recent posts from: EcoliHub blog, The Loom, Small Things Considered. Do you have a blog with an RSS feed that you'd like to add to our sources? Send us your URL. Or send us news items and we will add them.
The Loom:
by Carl Zimmer (6 days ago):
One of the most mind-blowing things I learned about while writing my book Microcosm: E. coli and the New Science of Life was the incredibly diversity of microbes that call our bodies home. These microbes outnumber our cells by about ten to one, and collectively they have thousands times more genes than found in the [...]
EcoliHub blog » E. coli news:
by jimhu (3 weeks ago):
Marshall Nirenberg, who shared the 1968 Nobel Prize in Physiology and Medicine for his role in deciphering the genetic code, died on January 15 of cancer.
Nirenberg and his coworkers used E. coli extracts for their key experiments examining the translation of natural and synthetic mRNAs. The most famous of these was the demonstration that [...]
Small Things Considered:
by Moselio Schaechter (2 months ago):
by Fred Neidhardt Van Gogh's Starry Night. (1889) The following is a personal account of the beginning years of what is now called proteomics. Odd that I, almost a Luddite, should be writing about the origin of a field initiated by a dramatic technical advance; I tend to avoid complex new scientific instruments and techniques. As a graduate student under...
From our events calendar.
Fri Feb 12 2010: 2nd ASM Conference on Mobile DNA - Abstract Deadline
EcoliHub Forum:
by (1 month ago):
Anyone going to the Microbial Stress Response Gordon Conference? Should we do an EcoliHub 2.0 poster there?
Statistics : Posted by jimhu • on Fri Jan 08, 2010 1:53 pm • Replies 0 • Views 14
EcoliHub Forum:
by (1 month ago):
Hi Rob,
Sorry for the slow response. I think your question about finding homologs with annotations is a very good one; for a lot of users, BLAST results give too many hits. One thing that helps is to restrict the databases used for BLAST and to filter the results. But in the long term, I think a better solution is to use a more rigorous phylogenetic analysis. That's on the agenda for things to develop in both the Gene Ontology Consortium work and in our Specific Aims for EcoliHub. The idea is to place annotations on nodes in phylogenetic trees where there is reasonable confidence, based on the experimentally annotated descendants of that common ancestor, that the annotations can be inferred for all other descendants.
That's one of the areas where the use of a common and carefully designed annotation vocabulary like Gene Ontology is very useful. It will allow us to say that annotation for B. subtilis, E. coli, and S. cerevisiae are all meant to say the same thing... or not.
Statistics : Posted by jimhu • on Fri Jan 08, 2010 1:52 am • Replies 4 • Views 60